Pharmaceutical companies are seeking male pill drugs
* Calcium channel blockers such as nifedipine – already approved for men with hypertension – may cause reversible infertility by altering the lipid metabolism of sperm so that they are not able to fertilize an egg [8].
* Miglustat -- also known by its trade name Zavesca –- is already approved for the treatment of Gaucher disease. In male mice, low doses of it cause reversible infertility by decreasing sperm motility [9].
* Researchers are developing analogs of Lonidamine, a drug developed as a cancer treatment which was an effective male contraceptive. Lonidamine’s toxicity disqualifies it as a potential contraceptive, but researchers have formulated several related compounds that are non-toxic and effective, such as Adjudin [10].